The Artemis II astronauts are bound for Earth after conducting a historic lunar fly-by and witnessing a total solar eclipse from their spacecraft
Commander Reid Wiseman says the Orion spacecraft crew "saw sights that no human has ever seen", while pilot Victor Glover says there are "no adjectives" to describe what they observed
The spacecraft reached its maximum distance from Earth - 252,756 miles (406,771km) - during the lunar fly-by. The crew had already broken the previous record for the furthest distance humans have travelled into space
The astronauts lost connection with Nasa while behind the Moon - the outage was expected and lasted around 40 minutes
"It is so great to hear from Earth again," said mission specialist Christina Koch as she broke the silence from the spacecraft
US President Donald Trump tells the astronauts that they have "made history and made all America really proud" - and invites them to the White House
The astronauts are due to splashdown in the Pacific Ocean off the west coast of the US at 20:07 eastern US time on Friday (01:07 BST Saturday)
We've just been hearing from the Artemis crew, who say they are ready to begin the lunar observation period in around 13 minutes.
Stick with us as we bring you the latest from onboard the Orion spacecraft.
Kelsey Young from mission control says the crew is 248,655 miles (400,171 km) from Earth. They will reach their furthest distance around 18:07 central time (22:07 GMT).
"At that time they will be in an LOS or a loss of signal with us on Earth as they'll be flying behind the Moon," she adds.
Astronaut Jeremy Hansen tells Nasa's Kelsey Young that the crew would like to name some craters on the Moon that they can currently see "both with our naked eye and with our long lens".
He asks Nasa to name one after Artemis II commander Reid Wiseman's late wife, Carroll, who died in 2020 of cancer.
They name another crater Integrity - after the Orion spacecraft which has carried them to the far side of the Moon.
"A number of years ago we started this journey.. and we lost a loved one and there's a feature on a really neat place on the moon... at certain times of the Moon's transit around Earth we will be able to see this from Earth," he says.
Jim Lovell, an astronaut in the Apollo 8 and 13 missions who had prerecorded a message for the Artemis crew before he died last year, also named a crater after his wife, Marilyn, in 1968.
Correction: An earlier version of this post incorrectly attributed the quotes above to Reid Wiseman.
Rebecca Morelle
Science editor, Houston
We were in mission control just a few hours ago - on a big screen at the front of the room, they were keeping track of the Apollo distance record, counting down the miles until they surpassed the distance set so long ago.
This is a major milestone for the team there, but there focus will be very much on the hours ahead as the crew travel even further into space.
On breaking the Apollo 13 record, one of the Artemis astronauts says: "We surpass the furthest distance humans have ever travelled from planet earth. We do so in honouring the extraordinary efforts and feats of our predecessors in human space exploration.
"We will continue our journey even further into space before Mother Earth succeeds in pulling us back to everything we hold dear."
He challenges this generation and the next "to make sure this record is not long-lived".
Rebecca Morelle
Science editor, reporting from Mission Control in Floria
Image source, NASAThey are now further than any human has ever been from Earth - a very long way away from home.
Watch: Moment Artemis II sets distance record
The Artemis II crew has broken the record for the furthest distance humans have travelled from Earth.
The record was previously set by the Apollo 13 crew in 1970 - the crew travelled 248,655 miles from Earth.
Artemis II will beat this record by about 4,102 miles, reaching a maximum distance of 252,757 miles.
We're expecting to hear from the crew on their reaction shortly.
We've just heard that there's been around a two-minute delay to when the Artemis crew will break the record of the furthest distance humans have travelled from the Earth.
We'll keep you up-to-date with the latest updates when we get them.
Nasa science officer Kelsey Young continues speaking to the crew.
She tells them that "around earthset and earthrise", when the crew is "viewing us back here at home", they'll be looking directly at Asia, Africa and Oceania.
"So I'm sure people watching from those places here on Earth will wanna give you a wave as you take their picture," she adds.
Earlier we heard from Artemis curation lead Juliane Gross, who explained that the crew will be able to see craters on the Moon such as Aristarchus Plateau and Grimaldi, and lunar plain Oceanus Procellarum.
Tara Mewawalla
Live reporter
We are moments away from one of the most important milestones of the of the Artemis II mission - the crew will break the record for the furthest distance humans have travelled from Earth.
Here is a look back at the other key moments of this mission:
Nasa Science Officer Kelsey Young has just checked in with the Artemis II crew.
"How do you hear me?" she asks.
One of the astronauts replies: "We hear you loud and clear. Kelsey, you've just got to know you're pulling us away from the Moon just now so let's go."
We're now hearing from the Artemis II crew, who are speaking to the science officer in Nasa's Mission Control Centre in Houston from onboard the Orion capsule.
This will be the crew's last chance to review the details of the mission before the flyby begins.
We're less than 30 minutes away from Nasa's Artemis II astronauts breaking a record that has stood since 1970.
They're set to go beyond 248,655 miles (400,171km) from Earth - the distance that was travelled by the Apollo 13 crew.
In a short while, the Artemis II astronauts are expected to surpass a record for travelling the furthest away from Earth than any humans before - set on Apollo 13 in 1970.
Today, the four-strong crew woke up to hear a special message recorded by astronaut Jim Lovell, who took part in the Apollo 8 and 13 missions. Lovell made the recording shortly before his death last year.
"Welcome to my old neighbourhood... I'm proud to pass that torch on to you as you swing around the Moon", he tells the astronauts.
"It's a historic day, and I know how busy you'll be, but don't forget to enjoy the view", he adds.
Image source, Universal Images via GettyAstronaut James Lovell, who was commander on the Apollo 13 mission in 1970, died last year
Pallab Ghosh
Science correspondent
Artemis II roared off the launch pad and into history on Thursday - and so far, the mission is doing exactly what Nasa hoped for.
“Flawless” was the word that the head of the Artemis programme, Dr Lori Glaze, used.
And the sights have not failed to astonish us all, from the moment the SLS rocket turned the Florida evening into a wall of white flame and thunder.
After a day in Earth orbit, Orion’s training wheels came off and the spacecraft with its four astronauts were blasted into an elliptical orbit around the Moon and back - seeing and sharing with us sights that had not been seen for more than fifty years.
Notably the view of the whole Earth from space: a stunning view of our planet hanging in the blackness of space.
The entire Earth hangs luminous in the blackness of space: deep blue oceans and swirling white clouds and bright atmosphere give it the appearance of a shimmering jewelled marble. An echo of the first colour image of Earth taken by the astronauts of Apollo 8 in 1968.
Back then the image that provided a moment of hope and optimism to a divided and war-torn world, and perhaps the new picture and the mission so far might have the same effect, especially as the best is yet to come with more spectacular images as the Orion space hurtles towards to its destination.
Image source, NASAAlison Francis
Senior science journalist
As the astronauts pass behind our celestial neighbour, the radio and laser signals that allow communication between the spacecraft and Earth, will be blocked by the Moon itself.
For about 40 minutes, the four astronauts will be totally alone.
They’ll spend the blackout dedicated to lunar observation – taking images, studying the Moon’s geology and simply gazing at its bleak beauty.
When they emerge and the signal is re-established, the world is expected to breathe a collective sigh of relief.
And the history-making astronauts will be able to share their incredible views with everyone back home.
Image source, European Photopress AgencyThe first moon landing took place in July 1969
Almost 60 years have passed since America's Apollo missions landed humans on the Moon for the first time in July 1969.
And, while Nasa's Artemis II crew won't make a lunar landing themselves, their mission over the next few days will to pave the way for the next human footsteps on the Moon.
During their trip the four astronauts will fly 6,400 miles (10,299km) beyond the far side of the Moon, which always faces away from the Earth - marking the first time this has taken place.
Nasa says that during this three-hour period, the crew will "analyse and photograph geologic features, such as impact craters and ancient lava flow", which will help future missions to explore the Moon's South Pole region.
Studies on the astronauts' health will also help Nasa to better understand how deep space travel influences the human mind and body, protecting astronauts on future lunar missions as well as travel to Mars.
If the crew pass safely around the Moon on this trip, Nasa's goal is for Artemis IV and V to become lunar landing missions - and is aiming for both to happen in 2028.
3...2...1...
Watch the all-important moment when the countdown concluded and Artemis II shot towards space, leaving spectators feeling its power through their entire body.
One BBC reporter described it as "spectacular" and difficult to fully take in.
Moment Artemis II mission blasts into space
BBC Visual Journalism Team
The four Artemis astronauts are spending 10 days cramped together in a space about the size of a minibus.
The Orion crew module has similarities to the ones used for the Apollo missions 50 years ago, but the interior is very different.
The weightless environment means they can make use of space that would otherwise be unusable - so the control panel can be on the “ceiling”.
The four seats the astronauts used during the launch are now packed away to give them more room.
Perhaps most important, there is a toilet tucked away under the floor. It’s not very private but has been designed to overcome the challenges of going to the bathroom in space.
And just above the toilet hatch is a step that doubles as a flywheel exercise machine - the astronauts will each pull on the cable for 30 minutes of resistance and cardiovascular training every day to help counter the physical effects of being in space.
Image source, ReutersNasa astronaut Christina Koch in the darkened Orion spacecraft on the third day of the agency's mission
Image source, ReutersKoch preparing for the lunar flyby inside the Orion spacecraft
Rebecca Morelle
Science editor, reporting from Mission Control
We always see the same side of the Moon from the Earth.
It’s tidally locked, which means that it takes the same amount of time for the Moon to spin on its axis as it does for the Moon to orbit once around the Earth.
The result is that one side perpetually faces us.
But don’t make the mistake of calling the side we don’t see the dark side. That comes from the name of a 1973 Pink Floyd Album - Dark Side of the Moon.
Because this side of the Moon isn’t dark - it gets illuminated by the Sun just like the near side is.
And you’ll see that when the Artemis astronauts return their images.